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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKD1 All Species: 32.42
Human Site: S625 Identified Species: 71.33
UniProt: Q15139 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15139 NP_002733.2 912 101704 S625 R F P T K Q E S Q L R N E V A
Chimpanzee Pan troglodytes XP_001170806 912 101668 S625 R F P T K Q E S Q L R N E V A
Rhesus Macaque Macaca mulatta XP_001114639 912 101836 S625 R F P T K Q E S Q L R N E V A
Dog Lupus familis XP_851386 884 99023 S597 R F P T K Q E S Q L R N E V A
Cat Felis silvestris
Mouse Mus musculus Q62101 918 102049 S631 R F P T K Q E S Q L R N E V A
Rat Rattus norvegicus Q9WTQ1 918 102025 S631 R F P T K Q E S Q L R N E V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512992 948 106688 S661 R F P T K Q E S Q L R N E V A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685219 878 98838 S591 R F P T K Q E S Q L R N E V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61267 476 54243 S236 A K I M K N L S H P C V V R M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45818 1070 120565 E822 R A E V Q I L E K V D H P G V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39009 513 58614 K273 S F V E P I S K S Q I Q K Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.9 92 N.A. 92.5 93.1 N.A. 81.3 N.A. N.A. 80.1 N.A. 20.1 N.A. 43.7 N.A.
Protein Similarity: 100 99.5 99.3 93.9 N.A. 95 95.4 N.A. 86.3 N.A. N.A. 86.7 N.A. 32 N.A. 56.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 100 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 100 N.A. 13.3 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 73 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 10 10 0 0 73 10 0 0 0 0 73 0 0 % E
% Phe: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % H
% Ile: 0 0 10 0 0 19 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 0 0 82 0 0 10 10 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 0 0 19 0 0 73 0 0 0 0 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 73 0 0 0 % N
% Pro: 0 0 73 0 10 0 0 0 0 10 0 0 10 0 0 % P
% Gln: 0 0 0 0 10 73 0 0 73 10 0 10 0 0 0 % Q
% Arg: 82 0 0 0 0 0 0 0 0 0 73 0 0 10 0 % R
% Ser: 10 0 0 0 0 0 10 82 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 10 0 0 0 0 0 10 0 10 10 73 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _